Revol LIMS delivers biospecimen inventory and lifecycle management, donor consent and ethics documentation, temperature-controlled storage monitoring, and built-in ISO 20387, ISBER, GCP, GDPR, and CAP biorepository accreditation compliance — in one purpose-built platform.
Biorepositories and biobanks manage one of the most complex and ethically sensitive sample collections in science. Whether your organisation supports population health research, oncology biobanking, rare disease registries, or clinical trial sample archiving, three challenges define this environment:
Revol LIMS maintains complete biospecimen provenance from collection event through processing, aliquoting, storage, distribution, and disposal — tracking every derivative sample type, every storage location, and every condition change across the full storage lifetime.
Revol LIMS maintains the consent status of every biospecimen and validates every sample access and distribution request against the applicable consent scope — preventing ethically non-compliant sample use and providing complete consent audit trail documentation.
Revol LIMS monitors biospecimen storage conditions continuously — with automated excursion alerts, chain-of-custody transport logging, and equipment failure escalation — protecting sample integrity and providing the documentation required by ISO 20387 and ISBER.
Revol LIMS manages biospecimen quality assessment from collection through long-term storage, and coordinates research sample distribution requests from researcher application through shipment and use reporting.
Across population biobanks, hospital-based biorepositories, rare disease registries, and clinical trial sample archives, the same critical operational and ethical challenges consistently create risk:
Without a real-time, position-level inventory system, biospecimen retrieval for research requests becomes a manual search exercise. Lost or mislabelled samples waste irreplaceable biological material and damage researcher confidence in the collection.
Donor consent records stored separately from sample inventory systems mean that consent status changes — withdrawals, amendments, new restrictions — are not automatically propagated to sample access controls, creating ethically non-compliant sample use risk.
Manual temperature logs checked periodically cannot detect or document short-duration excursions that compromise sample integrity. Without continuous monitoring and automated excursion documentation, sample quality disputes cannot be resolved with evidence.
Tracking the provenance of every aliquot generation, every derivative sample type, and every processing method change across thousands of specimens through spreadsheets leads to provenance gaps that make samples scientifically unusable.
Sample shipments to external researchers frequently disappear from the biobank’s view between dispatch and use reporting. Without a structured distribution management workflow, sample accountability obligations cannot be met.
Without configurable quality assessment workflows linked to storage records and research request gates, low-quality samples are distributed to researchers who then reject them — wasting irreplaceable material and research funding.
Biorepositories and biobanks face compliance obligations spanning international biobanking standards, national tissue legislation, clinical trial requirements, and data privacy regulation. Revol LIMS ensures continuous ethics and accreditation compliance across every applicable framework.
| ISO 20387:2018 (Biobanking) | How Revol LIMS Supports Compliance |
|---|---|
| ISBER Best Practices | Complete quality management system for testing and calibration: method management, measurement uncertainty, equipment calibration, personnel competency, proficiency testing, non-conformance, internal audit, and management review records. |
| GCP (ICH E6) | Calibration certificate review workflow confirming measurement traceability to national standards, scope and uncertainty adequacy, and reference standard linkage for every piece of accredited equipment. |
| ILAC G8:09/2019 (Measurement Uncertainty) | GUM-compliant uncertainty budget management with Type A and Type B component tracking, combined uncertainty calculation, and expanded uncertainty statement generation in every report and certificate. |
| GDPR (EU) / HIPAA (US) | Equipment verification and calibration records aligned to OIML recommendations for weighing instruments, measuring containers, and utility meters used in regulated trade applications. |
| Human Tissue Act 2004 (UK) | Uncertainty budget structure and calculation methodology aligned to EA-4/02 M:2022 Expression of the Uncertainty of Measurement in Calibration for calibration laboratory certificate generation. |
| NCI Best Practices for Biospecimen Resources | Configurable workflows and documentation aligned to NABL accreditation requirements under DAC-01 for testing and calibration laboratories seeking or maintaining NABL accreditation in India. |
| CAP Biorepository Accreditation | Flexible accreditation body-specific documentation configuration supporting supplementary requirements from major national accreditation bodies across North America, UK, Germany, and Australia. |
| ISO/IEC 17025:2017 (where applicable) | For biorepositories performing analytical testing on stored specimens, method validation, measurement uncertainty, equipment calibration, and proficiency testing documentation aligned to ISO 17025. |
| ALCOA+ Data Integrity | All biospecimen records, consent documents, and temperature logs are Attributable, Legible, Contemporaneous, Original, and Accurate — satisfying accreditation body assessors and ethics committee auditors. |
Tracks every biospecimen from collection through aliquoting, storage, distribution, and disposal with complete lifecycle provenance and position-level inventory.
Maintains donor consent profiles and validates every sample access request against applicable consent scope, with automatic quarantine on withdrawal.
Continuously monitors storage conditions with automated excursion alerts, transport logging, and cryogenic level monitoring to protect sample integrity.
Manages the complete research sample distribution cycle from researcher request through ethics approval, shipment, use reporting, and return.
Manages quality assessment workflows linked to storage records and research request gates to prevent distribution of non-viable specimens.
Surfaces intelligence that protects biospecimen integrity, consent compliance, and collection sustainability across the biobank.
| Feature | Revol LIMS | Legacy Vendors |
|---|---|---|
| Biospecimen Inventory | Real-time - position-level inventory with complete lifecycle provenance and virtual search by type, tissue, quality, and consent. | Spreadsheet inventory with no real-time updates; mislabelled or lost samples discovered only on physical search. |
| Consent Compliance | Automated — consent validation at every access request with real-time withdrawal quarantine across all affected aliquots. | Consent records stored separately from inventory; changes not propagated to access controls, creating ethically non-compliant use risk. |
| Temperature Monitoring | Continuous automated — monitoring with configurable excursion alerts, impact assessment, and transport logging. | Manual temperature logs checked periodically; short-duration excursions undetected and undocumented. |
| Research Distribution | Structured workflow : request, consent validation, ethics approval, quality gate, shipment documentation, and use reporting. | Distribution tracked in spreadsheets or email; accountability obligations to ethics committees unmet. |
| Quality Assessment | Configurable — QA workflows with quality-score-linked distribution gates preventing low-quality sample release. | Quality data recorded separately from inventory; low-quality samples distributed without systematic quality gate. |
| Implementation Time | 3–4 Months — with domain expertise in biorepository and biobank management environments. | 9–12 Months with heavy custom configuration and onsite consulting requirements. |
Revol LIMS gives biorepositories and biobanks the infrastructure to maintain complete biospecimen lifecycle provenance, enforce consent compliance at every sample access point, protect sample integrity through continuous storage monitoring, and satisfy ISO 20387, ISBER, and CAP accreditation requirements.
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Yes. Revol LIMS maintains position-level inventory tracking at the room, freezer, shelf, rack, box, and position levels, providing real-time visibility of every specimen’s physical location. Inventory search by specimen type, tissue, disease area, quality score, consent scope, and availability enables efficient fulfilment of research requests without manual physical searches.
Revol LIMS maintains a consent profile for every biospecimen collection, including consent type, scope, restrictions, and version. Every sample access, distribution, and research use request is validated against the applicable consent scope before approval. Consent withdrawals trigger automatic quarantine across all affected aliquots, and consent amendments are tracked with effective date and impacted sample identification.
Yes. Revol LIMS integrates with storage equipment temperature and humidity sensors to provide continuous monitoring with configurable alert thresholds. Automated excursion notifications are sent to the laboratory manager and backup contacts, and the system performs excursion impact assessment to identify and document all samples affected by a temperature deviation.
Yes. Revol LIMS supports a complete biobanking quality management system aligned to ISO 20387:2018, including biospecimen collection, processing, storage, quality assessment, distribution, ethics documentation, temperature monitoring, and equipment management for national accreditation body certification.
Yes. Revol LIMS manages the complete research distribution cycle from researcher application through consent and ethics validation, quality gate approval, shipment documentation with transport condition logging, use reporting obligations, and remaining sample return and reintegration tracking.
Revol LIMS is available as SaaS, PaaS, and on-premise deployments. For biorepositories with specific data sovereignty requirements under GDPR, national tissue legislation, or institutional data governance policies, on-premise or private cloud deployment options are fully supported.
